{"product_id":"recombinant-human-il-2rb-cd122-protein-fc-tagactive-pksh032572","title":"Recombinant Human IL-2RB\/CD122 Protein (Fc Tag)(Active) - PKSH032572","description":"\u003cp\u003eRecombinant Human IL-2RB\/CD122 Protein (Fc Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032572-10, PKSH032572-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL-2RB; CD122\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Interleukin-2 receptor subunit beta; IL2RB; IL-2 receptor subunit beta; IL-2R subunit beta; High affinity IL-2 receptor subunit beta; CD122\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P14784\u003c\/p\u003e\n\n\u003cp\u003eAccession: P14784\u003c\/p\u003e\n\n\u003cp\u003eBackground: Human IL-2RB; also known asinterleukin-2 receptor subunit beta; is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein; and has a 26 residue signal peptide; a 214 residue extracellular region; a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules; such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Human IL-2(Cat: PKSH032629) at 10μg\/ml(100 μl\/well) can bind Human IL-2RB-Fc. The ED50 of Human IL-2RB-Fc is 1. 37 ug\/mL\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala27-Asp239\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 51.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60-80 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43118142750899,"sku":"PKSH032572-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43118142783667,"sku":"PKSH032572-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7d52d5ce-7769-41da-8c5e-91a466265ecd.png?v=1709636996","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-2rb-cd122-protein-fc-tagactive-pksh032572","provider":"AFSBio Inc.","version":"1.0","type":"link"}