{"product_id":"recombinant-human-il-2rb-cd122-protein-his-tag-pksh032571","title":"Recombinant Human IL-2RB\/CD122 Protein (His Tag) - PKSH032571","description":"\u003cp\u003eRecombinant Human IL-2RB\/CD122 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032571-10, PKSH032571-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL-2RB; CD122\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Interleukin-2 receptor subunit beta; IL2RB; IL-2 receptor subunit beta; IL-2R subunit beta; High affinity IL-2 receptor subunit beta; CD122\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P14784\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P14784\u003c\/p\u003e\n\n\u003cp\u003eBackground: Human IL-2RB; also known asinterleukin-2 receptor subunit beta; is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein; and has a 26 residue signal peptide; a 214 residue extracellular region; a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules; such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala27-Asp239\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 25.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35-40 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068854730931,"sku":"PKSH032571-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068854763699,"sku":"PKSH032571-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_094cba83-5c89-47b4-8148-147b0d43bb39.png?v=1708598242","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-2rb-cd122-protein-his-tag-pksh032571","provider":"AFSBio Inc.","version":"1.0","type":"link"}