{"product_id":"recombinant-human-il-2rb-cd122-protein-rp00407","title":"Recombinant Human IL-2RB\/CD122 Protein - RP00407","description":"\u003cp\u003eRecombinant Human IL-2RB\/CD122 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20ug, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00407-20, RP00407-50, RP00407-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IL-2RB\/CD122 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ala27-Asp239) of human IL-2RB\/CD122 (Accession #P14784) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IL2RB, CD122, IL15RB, P70-75\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P14784\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3560\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha\/beta subunit heterodimer, while the high affinity form consists of an alpha\/beta\/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.\u003c\/p\u003e \n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: AVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKD\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20ug","offer_id":45198377386163,"sku":"RP00407-20","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198377418931,"sku":"RP00407-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198377451699,"sku":"RP00407-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_5448b701-cf3e-49a8-a6fd-425bd550c7e8.png?v=1766961435","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-2rb-cd122-protein-rp00407","provider":"AFSBio Inc.","version":"1.0","type":"link"}