{"product_id":"recombinant-human-il-7-receptor-subunit-alpha-il-7ra-cd127-c-6his-pksh033944","title":"Recombinant Human IL-7 Receptor Subunit  alpha\/IL-7RA\/CD127 (C-6His) - PKSH033944","description":"\u003cp\u003eRecombinant Human IL-7 Receptor Subunit  alpha\/IL-7RA\/CD127 (C-6His)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033944-10, PKSH033944-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL-7RA; CD127\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P16871\u003c\/p\u003e\n\n\u003cp\u003eAccession: P16871\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Glu21-Gly236\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 25.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 40-55 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43114002088115,"sku":"PKSH033944-10","price":152.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43114002120883,"sku":"PKSH033944-50","price":453.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_76503667-b676-41fd-b70b-c6730dfb3f6d.png?v=1709550070","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-7-receptor-subunit-alpha-il-7ra-cd127-c-6his-pksh033944","provider":"AFSBio Inc.","version":"1.0","type":"link"}