{"product_id":"recombinant-human-il17rc-protein-fc-tagactive-pksh031013","title":"Recombinant Human IL17RC Protein (Fc Tag)(Active) - PKSH031013","description":"\u003cp\u003eRecombinant Human IL17RC Protein (Fc Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH031013-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL17RC\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: IL17-RL; IL17RL; UNQ6118\/PRO20040\/PRO38901\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-hFc\u003c\/p\u003e\n\n\u003cp\u003eAccession: NP_116121.2\u003c\/p\u003e\n\n\u003cp\u003eBackground: Plexin domain-containing protein 1; also known as tumor endothelial marker 3; tumor endothelial marker 7 and PLXDC1 and TEM3; is a secreted; cytoplasm and single-pass type I membrane protein which belongs to theplexin family. PLXDC1 \/ TEM3 is detected in endothelial cells from colorectal cancer; and in endothelial cells from primary cancers of the lung; liver; pancreas; breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1 \/ TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1 \/ TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 \/ TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1 \/ TEM3 may be a molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy (PDR). PLXDC1 \/ TEM3 interacts with NID1. It may also interact with CTTN.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measured by its ability to bind with recombinant human IL17A-His in a functional ELISA.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Ala 454\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 75.3 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 100-120 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104289063091,"sku":"PKSH031013-100","price":1024.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_bb309267-70df-450d-a910-b6016aa969d8.png?v=1709293849","url":"https:\/\/afsbio.com\/products\/recombinant-human-il17rc-protein-fc-tagactive-pksh031013","provider":"AFSBio Inc.","version":"1.0","type":"link"}