{"product_id":"recombinant-human-il1rapl-2-protein-rp01820","title":"Recombinant Human IL1RAPL-2 Protein - RP01820","description":"\u003cp\u003eRecombinant Human IL1RAPL-2 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01820-10, RP01820-20, RP01820-50, RP01820-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IL1RAPL-2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr17-Glu356) of human IL1RAPL-2 (Accession #NP_059112.1) fused with hFc and 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IL1R9; IL-1R9; TIGIRR-1; IL1RAPL-2; IL1RAPL2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9NP60\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 26280\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. IL-1R9\/IL1RAPL2 shows restricted expression in the fetal brain and is highly homologous to IL1RAPL, which is reportedly involved in nonsyndromic X-linked mental retardation. IL-1R9\/IL1RAPL2 is highly homologous to IL-1R8. Both forms have no known ligands and receptors are found in the fetal brain. IL-1R9\/IL1RAPL2 may function as a negative receptor. Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins. IL-1R9\/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci, and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u0026amp;6*His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: TNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIE\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198268203187,"sku":"RP01820-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198268235955,"sku":"RP01820-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198268268723,"sku":"RP01820-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198268301491,"sku":"RP01820-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_a80dcec3-4975-4116-b1ef-b81499ec842f.png?v=1766959925","url":"https:\/\/afsbio.com\/products\/recombinant-human-il1rapl-2-protein-rp01820","provider":"AFSBio Inc.","version":"1.0","type":"link"}