{"product_id":"recombinant-human-interferon-omega-1-ifnw1-protein-rp01752","title":"Recombinant Human Interferon omega-1\/IFNW1 Protein - RP01752","description":"\u003cp\u003eRecombinant Human Interferon omega-1\/IFNW1 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01752-10, RP01752-20, RP01752-50, RP01752-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Interferon omega-1\/IFNW1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly23-Ser195) of human Interferon omega-1\/IFNW1 (Accession #NP_002168.1) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Interferon omega-1; IFNW1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P05000\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3467\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide sequence. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type II IFN and is specific for the type II IFN receptor. Human IFN-ω, was identified by three independent groups in 1985 and is structurally related to IFN-α and -β. Both human IFN-ω and IFN-α are produced by virally induced leukocytes and have similar antiviral activities on human cell lines, and a sizeable proportion (at least 1%) of the total antiviral activity of leukocyte IFN is contributed by IFN-ωl. Also, it was reported that IFN-ω could inhibit the growth of human tumors in vivo.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 0.13-0.54 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: GCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFRFPQEMVKGSQLQKAHVMSVLHEMLQQIFSLFHTERSSAAWNMTLLDQLHTGLHQQLQHLETCLLQVVGEGESAGAISSPALTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLSTNMQERLRSKDRDLGSS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198333804723,"sku":"RP01752-10","price":182.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198333837491,"sku":"RP01752-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198333870259,"sku":"RP01752-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198333903027,"sku":"RP01752-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_d21e0129-ba16-4fc0-96c1-7136b0828002.png?v=1766960709","url":"https:\/\/afsbio.com\/products\/recombinant-human-interferon-omega-1-ifnw1-protein-rp01752","provider":"AFSBio Inc.","version":"1.0","type":"link"}