{"product_id":"recombinant-human-interleukin-13-il-13-c-avi-6his-biotinylated-pksh034033","title":"Recombinant Human Interleukin-13\/IL-13 (C-Avi-6His) Biotinylated - PKSH034033","description":"\u003cp\u003eRecombinant Human Interleukin-13\/IL-13 (C-Avi-6His) Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH034033-20, PKSH034033-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Interleukin-13; IL-13\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Interleukin-13; IL-13\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Avi-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: AAK53823\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gly21-Asn132\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 15.2 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 22-35 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43149088063667,"sku":"PKSH034033-20","price":478.8,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43149088096435,"sku":"PKSH034033-100","price":1293.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_27b706e9-5797-4542-b85a-c1f28b478e5d.png?v=1710340470","url":"https:\/\/afsbio.com\/products\/recombinant-human-interleukin-13-il-13-c-avi-6his-biotinylated-pksh034033","provider":"AFSBio Inc.","version":"1.0","type":"link"}