{"product_id":"recombinant-human-interleukin-13-il-13-protein-fc-tagactive-pksh032457","title":"Recombinant Human Interleukin-13\/IL-13 Protein (Fc Tag)(Active) - PKSH032457","description":"Recombinant Human Interleukin-13\/IL-13 Protein (Fc Tag)(Active)\n\nSize: 50μg\n\nCatalogue Number: PKSH032457-50\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: Interleukin-13; IL-13\n\nTarget Symptom: ALRH; IL-13; P600; IL13\n\nTarget Species: Human\n\nExpression Host: HEK293 Cells\n\nApplication: ELISA\n\nFusion Tag: N-hFc\n\nAccession: AAK53823.1\n\nBackground: Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13\/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα ) and at least one of two known IL-13-specific binding chains (IL-13 Rα 1 and IL-13 Rα 2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.\n\nActivity: Immobilized recombinant human IL13RA2 at 8 μg\/ml (100 μl\/well) can bind IL13 with a linear range of 0.25-8.0 ng\/ml.\n\nSequence: Gly 21-Asn 132\n\nPurity: \u0026gt; 98 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile PBS, pH 7.4\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\n\nCalculated MW: 39 kDa\n\nObserved MW: 50-55 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104260587699,"sku":"PKSH032457-50","price":935.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4ec0c310-0aa5-4056-a14e-bacb52930d70.png?v=1709293257","url":"https:\/\/afsbio.com\/products\/recombinant-human-interleukin-13-il-13-protein-fc-tagactive-pksh032457","provider":"AFSBio Inc.","version":"1.0","type":"link"}