{"product_id":"recombinant-human-interleukin-17f-rhuil-17f-pr1064","title":"Recombinant Human Interleukin-17F (rHuIL-17F) - PR1064","description":"\u003cp\u003eRecombinant Human Interleukin-17F (rHuIL-17F)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1064-5, PR1064-25\u003c\/p\u003e\n\n\u003cp\u003eSizes: 5µg, 25µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: A disulfide-linked homodimer of 30.1kDa, consisting of two 133 amino acid polypeptide chains.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Measured by its ability to induce IL-6 production by NHDF cells, it’s fully biologically active when compared to standard.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST\u003cbr\u003e\n SPWNYt VTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV\u003cbr\u003e\n VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rHuIL-17F as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 4 mM HCl to a concentration of 0.1mg\/ml. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Human IL-17F is synthesized as a 153 aa precursor with a 20 aa signal sequence and a 133 aa mature region. Like IL-17A, IL-17F contains one potential site for N-linked glycosylation. IL-17A and IL-17F share 50% aa sequence identity. IL17-F homodimer is produced by an activated subset of CD4+ T cells, termed Th17. IL17-F has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"5µg","offer_id":42882225963187,"sku":"PR1064-5","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"25µg","offer_id":42882225995955,"sku":"PR1064-25","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_669c93c2-e2f4-4151-b4fe-bad63bc89ac3.jpg?v=1702049629","url":"https:\/\/afsbio.com\/products\/recombinant-human-interleukin-17f-rhuil-17f-pr1064","provider":"AFSBio Inc.","version":"1.0","type":"link"}