{"product_id":"recombinant-human-interleukin-2-il-2-protein-e-coli-active-pksh033425","title":"Recombinant Human Interleukin-2\/IL-2 Protein (E.coli, Active) - PKSH033425","description":"\u003cp\u003eRecombinant Human Interleukin-2\/IL-2 Protein (E.coli, Active)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH033425-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Interleukin-2; IL-2\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL5\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eApplication: Cell culture\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: None\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P60568\u003c\/p\u003e\n\n\u003cp\u003eAccession: P60568\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system; belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2\/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes.\u003c\/p\u003e\n\n\u003cp\u003eActivity: 1. Measure by its ability to induce proliferation in CTLL-2 cells. The ED50 for this effect is \u0026lt; 0.2 ng\/mL The specific activity of recombinant human IL-2 is approximately \u0026gt; 2. 5 x10^7 IU\/mg. \u003cbr\u003e\n2. Measure by its ability to induce proliferation in NK cells. The ED50 for this effect is \u0026lt; 46ng\/mL.\u003c\/p\u003e \n\n\u003cp\u003eSequence: Ala21-Thr153\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 10mM sodium citrate, pH 4.0\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 15.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 14 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43107265151155,"sku":"PKSH033425-100","price":348.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_702a347e-df51-4bc8-bdaf-f626458529df.png?v=1709382170","url":"https:\/\/afsbio.com\/products\/recombinant-human-interleukin-2-il-2-protein-e-coli-active-pksh033425","provider":"AFSBio Inc.","version":"1.0","type":"link"}