{"product_id":"recombinant-human-ippi2-idi2-protein-his-tag-pksh032661","title":"Recombinant Human IPPI2\/IDI2 Protein (His Tag) - PKSH032661","description":"\u003cp\u003eRecombinant Human IPPI2\/IDI2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032661-10, PKSH032661-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IPPI2; IDI2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Isopentenyl-Diphosphate Delta-Isomerase 2; Isopentenyl Pyrophosphate Isomerase 2; IPP Isomerase 2; IPPI2; IDI2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9BXS1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cardiovascular; Cancer; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9BXS1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Isopentenyl Pyrophosphate Isomerase 2 (IDI2) belongs to the IPP isomerase type 1 family. Both isozymes, IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway. IDI2 is expressed in skeletal muscle, which contains one nudix hydrolase domain. IDI2 binds one magnesium per subunit. IDI2 catalyzes the 1, 3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). It is reported that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPAR-α.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Val227\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 0.1mM PMSF, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28.9 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 28-31 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068870852787,"sku":"PKSH032661-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068870885555,"sku":"PKSH032661-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_698da5e4-09a3-455f-b30d-919f9f978c57.png?v=1708598386","url":"https:\/\/afsbio.com\/products\/recombinant-human-ippi2-idi2-protein-his-tag-pksh032661","provider":"AFSBio Inc.","version":"1.0","type":"link"}