{"product_id":"recombinant-human-lamp1-cd107a-protein-fc-tagactive-pksh032683","title":"Recombinant Human LAMP1\/CD107a Protein (Fc Tag)(Active) - PKSH032683","description":"\u003cp\u003eRecombinant Human LAMP1\/CD107a Protein (Fc Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032683-10, PKSH032683-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: LAMP1; CD107a\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Lysosome-Associated Membrane Glycoprotein 1; LAMP-1; Lysosome-Associated Membrane Protein 1; CD107 Antigen-Like Family Member A; CD107a; LAMP1; CD107a; LAMPA; LGP120\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; Tags \u0026amp; Cell Markers; Neuroscience; Cancer; metabolism; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P11279\u003c\/p\u003e\n\n\u003cp\u003eAccession: P11279\u003c\/p\u003e\n\n\u003cp\u003eBackground: Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes; endosomes; and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers; as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium; therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Human LGALS3(Cat#PKSH032474) at 2μg\/ml (100 μl\/well) can bind Human LAMP1-Fc. The ED50 of Human LAMP1-Fc is 1-5 ug\/ml.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala29-Met382\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 65.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 106 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43118148321459,"sku":"PKSH032683-10","price":163.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43118148354227,"sku":"PKSH032683-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_cb572d08-700e-42a0-a5dd-825b0b2e7d35.png?v=1709637089","url":"https:\/\/afsbio.com\/products\/recombinant-human-lamp1-cd107a-protein-fc-tagactive-pksh032683","provider":"AFSBio Inc.","version":"1.0","type":"link"}