{"product_id":"recombinant-human-long-r3-insulin-like-growth-factor-1-receptor-grade-rhu-lr3igf-1-pr1081","title":"Recombinant Human Long R3 Insulin-like Growth factor-1 Receptor Grade (rHu LR3IGF-1) - PR1081","description":"\u003cp\u003eRecombinant Human Long R3 Insulin-like Growth factor-1 Receptor Grade (rHu LR3IGF-1)\u003c\/p\u003e\n\n\n\u003cp\u003eCatalogue Numbers: PR1081-20, PR1081-100, PR1081-1000\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20µg, 100µg, 1.0mg (Contact us for the 1.0mg option)\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight:Approximately 9.1 kDa, a single non-glycosylated polypeptide chain containing 83 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. \u003cbr\u003e\nThe ED50 as determined by the stimulation of protein synthesis in L6 myoblasts  is less then 10 ng\/ml.\u003c\/p\u003e\n\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.0.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR \u003cbr\u003e\nAPQTGIVDEC CFRSCDLRRL  EMYCAPLKPA KSA\u003c\/p\u003e\n\n\n\u003cp\u003eEndotoxin: Less than 50EU\/mg of rHuLR3IGF-1 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.   Made  in China\u003c\/p\u003e\n\n\u003cp\u003eInsulin-like growth factor-1 (IGF-1) is the principal hormonal mediator of statural growth. Under normal circumstances, growth hormone (GH) binds to its receptor in the liver, and other tissues, and stimulates the synthesis\/secretion of IGF-1. In target tissues, the Type 1 IGF receptor, which is homologous to the insulin receptor, is activated by IGF-1, leading to intracellular signaling which stimulates multiple processes leading to statural growth. The metabolic actions of IGF-1 are in part directed at stimulating the uptake of glucose, fatty acids, and amino acids so that metabolism supports growing tissues. The LR3 is a long-term analog of human IGF-1, specifically designed and manufactured for mammalian cell culture to support large-scale manufacturing of recombinant biopharmaceuticals.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"20µg","offer_id":42880591954099,"sku":"PR1081-20","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µg","offer_id":42880591986867,"sku":"PR1081-100","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a9117657-d5f5-47ba-b34f-0dbb2b64116a.jpg?v=1701982017","url":"https:\/\/afsbio.com\/products\/recombinant-human-long-r3-insulin-like-growth-factor-1-receptor-grade-rhu-lr3igf-1-pr1081","provider":"AFSBio Inc.","version":"1.0","type":"link"}