{"product_id":"recombinant-human-map1d-protein-his-tag-pksh032749","title":"Recombinant Human MAP1D Protein (His Tag) - PKSH032749","description":"\u003cp\u003eRecombinant Human MAP1D Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032749-10, PKSH032749-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MAP1D\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Methionine Aminopeptidase 1D Mitochondrial; Methionyl Aminopeptidase Type 1D Mitochondrial; METAP1D; MAP1D; MAP 1D; MetAP 1D; Metap1l\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q6UB28\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; epigenetics and nuclear signal;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His \u0026amp; C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q6UB28\u003c\/p\u003e\n\n\u003cp\u003eBackground: Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Arg44-Ala335\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 35.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35-40 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068890808499,"sku":"PKSH032749-10","price":385.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068890841267,"sku":"PKSH032749-50","price":735.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8834a4ac-1491-4f03-87e0-55e490bebfed.png?v=1708598606","url":"https:\/\/afsbio.com\/products\/recombinant-human-map1d-protein-his-tag-pksh032749","provider":"AFSBio Inc.","version":"1.0","type":"link"}