{"product_id":"recombinant-human-mature-bmp-9-gdf-2-protein-rp00722","title":"Recombinant Human Mature BMP-9\/GDF-2 Protein - RP00722","description":"\u003cp\u003eRecombinant Human Mature BMP-9\/GDF-2 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00722-10, RP00722-20, RP00722-50, RP00722-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Mature BMP-9\/GDF-2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser320-Arg429) of Human Mature BMP-9\/GDF-2 (Accession # Q9UK05) fused with no tag.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: GDF2, BMP9, Growth\/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UK05\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2658\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: BMP-9 is a member of the BMP subgroup of the TGF-beta superfamily proteins that signal through heterodimeric complexes composed of type I and type II BMP receptors. GDF-2 Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin\/ENG. ALK1 is a signalling receptor for bone morphogenetic protein-9 (BMP-9) in endothelial cells (ECs). BMP-9 bound with high affinity to ALK1 and endoglin, and weakly to the type-I receptor ALK2 and to the BMP type-II receptor (BMPR-II) and activin type-II receptor (ActR-II) in transfected COS cells.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: NO-Tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: SAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198241857715,"sku":"RP00722-10","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198241890483,"sku":"RP00722-20","price":392.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198241923251,"sku":"RP00722-50","price":630.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198241956019,"sku":"RP00722-100","price":1008.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_0ffbfe0b-ad87-4051-aa65-f2a089f1d31e.png?v=1766959626","url":"https:\/\/afsbio.com\/products\/recombinant-human-mature-bmp-9-gdf-2-protein-rp00722","provider":"AFSBio Inc.","version":"1.0","type":"link"}