{"product_id":"recombinant-human-mlp3b-map1lc3b-protein-his-tag-pdeh100241","title":"Recombinant Human MLP3B\/MAP1LC3B protein (His tag) - PDEH100241","description":"\u003cp\u003eRecombinant Human MLP3B\/MAP1LC3B protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEH100241-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MLP3B; MAP1LC3B\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: MLP3B; ATG8F; Autophagy related protein LC3 A; Autophagy related ubiquitin like modifier LC3 A; Autophagy related ubiquitin like modifier LC3 B; LC3; MAP1 light chain 3 like protein 1; MAP1 light chain 3 like protein 2; MAP1A\/1B light chain 3 A; MAP1A\/1BLC3; MAP1ALC3; MAP\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9GZQ8\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cardiovascular; Cancer; Neuroscience; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-10His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9GZQ8\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria. While LC3s are involved in elongation of the phagophore membrane, the GABARAP\/GATE-16 subfamily is essential for a later stage in autophagosome maturation.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Val 125\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 13.64 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 18 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43072326664371,"sku":"PDEH100241-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_711d6374-f3f0-43e9-9477-efb3ae4f40e8.png?v=1708685660","url":"https:\/\/afsbio.com\/products\/recombinant-human-mlp3b-map1lc3b-protein-his-tag-pdeh100241","provider":"AFSBio Inc.","version":"1.0","type":"link"}