{"product_id":"recombinant-human-mmp-10-protein-rp01969","title":"Recombinant Human MMP-10 Protein - RP01969","description":"\u003cp\u003eRecombinant Human MMP-10 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01969-10, RP01969-20, RP01969-50, RP01969-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human MMP-10 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr18-Cys476) of Human MMP-10 (Accession #NP_002416.1) fused with His at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: MMP10, STMY2, Stromelysin-2, SL-2, EC:3.4.24.22, Matrix metalloproteinase-10, MMP-10, Transin-2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P09238\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4319\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-10 degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP-10 can activate other MMPs such as MMP-1 and MMP-8. MMP-10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP-10 may be divided into four distinct domains: a pro-domain which is cleaved upon activation, a catalytic domain containing the zinc binding site; a short linker region, and a carboxyl terminal hemopexin-like domain.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 150 mM NaCl, 5 mM CaCl2, 50 mM Tris, pH 7.5.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: YPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198270693555,"sku":"RP01969-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198270726323,"sku":"RP01969-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198270759091,"sku":"RP01969-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198270791859,"sku":"RP01969-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_b0656d26-ca63-454b-9f77-dbcf69976e45.png?v=1766959952","url":"https:\/\/afsbio.com\/products\/recombinant-human-mmp-10-protein-rp01969","provider":"AFSBio Inc.","version":"1.0","type":"link"}