{"product_id":"recombinant-human-mouse-fgf-8b-protein-rp01659","title":"Recombinant Human\/Mouse FGF-8B Protein - RP01659","description":"\u003cp\u003eRecombinant Human\/Mouse FGF-8B Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: RP01659-10, RP01659-20\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human\/Mouse FGF-8B Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln23-Arg215) of human FGF-8B (Accession #NP_006110.1) fused with and a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: HH6; AIGF; KAL6; FGF-8; HBGF-8; FGF8B\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P55075-3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2253 (B)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\/Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: QVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198349959347,"sku":"RP01659-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198349992115,"sku":"RP01659-20","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_a2094af7-bf3c-4ff4-ba1f-1bb40fa21771.png?v=1766960911","url":"https:\/\/afsbio.com\/products\/recombinant-human-mouse-fgf-8b-protein-rp01659","provider":"AFSBio Inc.","version":"1.0","type":"link"}