{"product_id":"recombinant-human-mouse-rat-mature-bmp-2-protein-rp02510s","title":"Recombinant Human\/Mouse\/Rat mature BMP-2 Protein - RP02510S","description":"\u003cp\u003eRecombinant Human\/Mouse\/Rat mature BMP-2 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP02510S-10, RP02510S-20, RP02510S-50, RP02510S-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human\/Mouse\/Rat mature BMP-2 Protein is produced by Escherichia coli expression system. The target protein is expressed with sequence (Ala284-Arg396) of Human\/Mouse\/Rat BMP-2 (NP_001191.1) fused with no tag.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: BDA2, BMP2A, BMP2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P12643\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 650\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human,Mouse,Rat\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: BMP-2 like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is also involved in cardiac cell differentiation and epithelial to mesenchymal transition. Like many other proteins from the BMP family, BMP-2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2 may be involved in white adipogenesis and may have metabolic effects.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.The ED50 for this effect is 24.59-98.36 ng\/mL, corresponding to a specific activity of 1.02×10^4 ~4.07×10^4 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: E.coli\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 0.1% TFA, 30% ACN. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: AKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198341898419,"sku":"RP02510S-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198341931187,"sku":"RP02510S-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198341963955,"sku":"RP02510S-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198341996723,"sku":"RP02510S-100","price":630.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_4c8ff33a-d846-4bcf-a6a5-8c8b43253a84.png?v=1766960897","url":"https:\/\/afsbio.com\/products\/recombinant-human-mouse-rat-mature-bmp-2-protein-rp02510s","provider":"AFSBio Inc.","version":"1.0","type":"link"}