{"product_id":"recombinant-human-natriuretic-peptides-b-nppb-protein-his-tag-pksh033585","title":"Recombinant Human Natriuretic Peptides B\/NPPB Protein (His Tag) - PKSH033585","description":"\u003cp\u003eRecombinant Human Natriuretic Peptides B\/NPPB Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033585-10, PKSH033585-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NPPB\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Natriuretic Peptides B; Gamma-Brain Natriuretic Peptide; NPPB\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; Cardiovascular; Neuroscience;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P16860\u003c\/p\u003e\n\n\u003cp\u003eAccession: P16860\u003c\/p\u003e\n\n\u003cp\u003eBackground: Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions; such as diuresis; natriuresis; vasorelaxation; which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water; improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.\u003c\/p\u003e\n\n\u003cp\u003eSequence: His27-His134\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, 1mM DTT, 20% Glycerol, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 14.2 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 16 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113972007091,"sku":"PKSH033585-10","price":385.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113972039859,"sku":"PKSH033585-50","price":735.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1b135e4e-6b03-42d8-b351-7f4ec5651149.png?v=1709549415","url":"https:\/\/afsbio.com\/products\/recombinant-human-natriuretic-peptides-b-nppb-protein-his-tag-pksh033585","provider":"AFSBio Inc.","version":"1.0","type":"link"}