{"product_id":"recombinant-human-nectin-3-pvrl3-cd113-protein-rp00984","title":"Recombinant Human Nectin-3\/PVRL3\/CD113 Protein - RP00984","description":"\u003cp\u003eRecombinant Human Nectin-3\/PVRL3\/CD113 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00984-10, RP00984-20, RP00984-50, RP00984-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Nectin-3\/PVRL3\/CD113 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gly 58 - Asp 400 ) of human Nectin 3 (Accession #NP_056295) fused with an Fc, 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CD113, CDw113, nectin 3, poliovirus receptor related 3, PPR3, PRR3, PVRL3, PVRR3, PVRL3, NECTIN3, CDW113, NECTIN-3, PPR3, PRR3, PVRR3, nectin-3\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9NQS3-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 25945\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This protein is a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Nectin-1 at 3 μg\/mL (100 μL\/well) can bind Recombinant Human Nectin-3 with a linear range of 180-720 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u0026amp;His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: GPIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDD\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198314963123,"sku":"RP00984-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198314995891,"sku":"RP00984-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198315028659,"sku":"RP00984-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198315061427,"sku":"RP00984-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_fa34892c-bc1e-4e30-8c02-c9cebc9ab11f.png?v=1766960505","url":"https:\/\/afsbio.com\/products\/recombinant-human-nectin-3-pvrl3-cd113-protein-rp00984","provider":"AFSBio Inc.","version":"1.0","type":"link"}