{"product_id":"recombinant-human-neurogranin-nrgn-protein-rp01814","title":"Recombinant Human Neurogranin\/NRGN Protein - RP01814","description":"\u003cp\u003eRecombinant Human Neurogranin\/NRGN Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01814-10, RP01814-20, RP01814-50, RP01814-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Neurogranin\/NRGN Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp2-Asp78) of human NRGN\/Neurogranin (Accession #) fused with hFc tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: RC3; hng; NRGN; Neurogranin\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q92686\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4900\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Neurogranin is as a small protein encoded by the NRGN gene. it is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin is the main postsynaptic protein regulating the availability of calmodulin, binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. It is a potential biomarker of neurological and mental diseases.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFC\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 20mM Tris 150mM Nacl, pH 7.5.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: DCCTENACSKPDDDILDIPLDDPGANAAAAKIQASFRGHMARKKIKSGERGRKGPGPGGPGGAGVARGGAGGGPSGD\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198252179635,"sku":"RP01814-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198252212403,"sku":"RP01814-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198252245171,"sku":"RP01814-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198252277939,"sku":"RP01814-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_5f318ac2-f116-4c62-9bba-a79f483413b2.png?v=1766959752","url":"https:\/\/afsbio.com\/products\/recombinant-human-neurogranin-nrgn-protein-rp01814","provider":"AFSBio Inc.","version":"1.0","type":"link"}