{"product_id":"recombinant-human-neuropilin-1-nrp1-vegf165r-cd304-protein-rp00137","title":"Recombinant Human Neuropilin-1\/NRP1\/VEGF165R\/CD304 Protein - RP00137","description":"\u003cp\u003eRecombinant Human Neuropilin-1\/NRP1\/VEGF165R\/CD304 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20ug, 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00137-10, RP00137-20, RP00137-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Neuropilin-1\/NRP1\/VEGF165R\/CD304 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Phe22-Lys644) of human Neuropilin-1\/NRP1 (Accession #NP_001019799) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: BDCA4, CD304, NP1, NRP, VEGF165R, Neuropilin-1, NRP1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O14786\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8829\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V\/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human NRP1 Protein at 2 μg\/mL (100 μL\/well) can bind NRP1 Rabbit pAb with a linear range of 1.9-98.96 ng\/mL.|2.Measured by its binding ability in a functional ELISA.Immobilized human VEGF165 at 1μg\/mL (25 μL\/well) can bind Human CD304 with a linear range of 0.46-15.8ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: FRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSYINEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLVDECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSGIK\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198367719603,"sku":"RP00137-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198367752371,"sku":"RP00137-20","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198367785139,"sku":"RP00137-50","price":490.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_3aa838fe-eeff-4d80-91f1-ecddbe6bf6af.png?v=1766961276","url":"https:\/\/afsbio.com\/products\/recombinant-human-neuropilin-1-nrp1-vegf165r-cd304-protein-rp00137","provider":"AFSBio Inc.","version":"1.0","type":"link"}