{"product_id":"recombinant-human-neurotrophin-3-ngf-2-nt-3-protein-rp00496","title":"Recombinant Human Neurotrophin-3\/NGF-2\/NT-3 Protein - RP00496","description":"\u003cp\u003eRecombinant Human Neurotrophin-3\/NGF-2\/NT-3 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00496-10, RP00496-20, RP00496-50, RP00496-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Neurotrophin-3\/NGF-2\/NT-3 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Tyr139-Thr257) of Human Neurotrophin-3\/NGF-2\/NT-3 (Accession # P20783) fused with No-Tag.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: NTF3, Neurotrophin-3, NT-3, HDNF, Nerve growth factor 2, NGF-2, Neurotrophic factor\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P20783\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4908\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β -NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptideand a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequencesof mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survivalof specific neuronal subpopulations in both the central as well as the peripheral nervous systems.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA.Immobilized Recombinant Human TrkB (Catalog: RP00290) at 2μg\/mL (100 μL\/well) can bind Recombinant Human Neurotrophin-3\/NGF-2\/NT-3 with a linear range of 1.95-35.5 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: No-Tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 5.2.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: YAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198337671347,"sku":"RP00496-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198337704115,"sku":"RP00496-20","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198337736883,"sku":"RP00496-50","price":490.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198337769651,"sku":"RP00496-100","price":784.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_befb3785-53a9-405e-89fb-d4b0671e5e2d.png?v=1766960760","url":"https:\/\/afsbio.com\/products\/recombinant-human-neurotrophin-3-ngf-2-nt-3-protein-rp00496","provider":"AFSBio Inc.","version":"1.0","type":"link"}