{"product_id":"recombinant-human-nkg2a-cd94-heterodimer-n-8his-flag-ept243","title":"Recombinant Human NKG2A \u0026 CD94 Heterodimer (N-8His-Flag) - EPT243","description":"\u003cp\u003eRecombinant Human NKG2A \u0026amp; CD94 Heterodimer (N-8His-Flag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: EPT243-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NKG2-A\/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D member 1 (KLRD1), is expressed on the surface of natural killer cells in the innate immune system. CD94 Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Can form disulfide-bonded heterodimer with NKG2 family members. The CD94\/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names:  NKG2A\u0026amp;CD94 Heterodimer; KLRC1\u0026amp;CD94 Heterodimer; CD159A\u0026amp;KLRD1 Heterodimer\u003c\/p\u003e \n\n\u003cp\u003eDescription: Recombinant Human Human NKG2A \u0026amp; CD94 Heterodimer is produced by our Mammalian expression system and the target gene encoding Arg100-Leu233 \u0026amp; Ser34-Ile179 is expressed with a 8His, Flag tag at the N-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAccession: P26715\u0026amp;Q13241\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 34.4 KDa\u003c\/p\u003e\n\n\u003cp\u003eApparent Molecular Weight: 25-40 KDa, reducing conditions\u003c\/p\u003e\n\n\u003cp\u003eStorage Condition: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003ePurity: Greater than 95% as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 0.1 ng\/µg (1 EU\/µg) as determined by LAL test.\u003c\/p\u003e\n\n\u003cp\u003eRedissolve: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg\/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. \u003c\/p\u003e\n\n\u003cp\u003eDelivery Condition: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"Default Title","offer_id":45201917706419,"sku":"EPT243-50","price":656.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_11e0bee8-b434-4a31-b26d-d8086d9dc4d1.png?v=1767117777","url":"https:\/\/afsbio.com\/products\/recombinant-human-nkg2a-cd94-heterodimer-n-8his-flag-ept243","provider":"AFSBio Inc.","version":"1.0","type":"link"}