{"product_id":"recombinant-human-nkg2a-cd94-heterodimer-protein-his-flag-tag-pksh032812","title":"Recombinant Human NKG2A \u0026 CD94 Heterodimer Protein (His \u0026 Flag Tag) - PKSH032812","description":"\u003cp\u003eRecombinant Human NKG2A \u0026amp; CD94 Heterodimer Protein (His \u0026amp; Flag Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032812-10, PKSH032812-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NKG2A \u0026amp; CD94 Heterodimer\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: NKG2A\u0026amp;CD94 Heterodimer; KLRC1\u0026amp;CD94 Heterodimer; CD159A\u0026amp;KLRD1 Heterodimer\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P26715\u0026amp;Q13241\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-8His \u0026amp; N-Flag\u003c\/p\u003e\n\n\u003cp\u003eAccession: P26715\u0026amp;Q13241\u003c\/p\u003e\n\n\u003cp\u003eBackground: NKG2-A\/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D member 1 (KLRD1), is expressed on the surface of natural killer cells in the innate immune system. CD94 Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Can form disulfide-bonded heterodimer with NKG2 family members. The CD94\/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Arg100-Leu233 \u0026amp; Ser34-Ile179\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 34.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 25-40 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068734996659,"sku":"PKSH032812-10","price":163.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068735029427,"sku":"PKSH032812-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_606987be-d633-4856-ba55-55bd1ee701b2.png?v=1708597233","url":"https:\/\/afsbio.com\/products\/recombinant-human-nkg2a-cd94-heterodimer-protein-his-flag-tag-pksh032812","provider":"AFSBio Inc.","version":"1.0","type":"link"}