{"product_id":"recombinant-human-nkp30-ncr3-protein-his-tag-pdmh100134","title":"Recombinant Human NKp30\/NCR3 protein (His tag) - PDMH100134","description":"\u003cp\u003eRecombinant Human NKp30\/NCR3 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDMH100134-20, PDMH100134-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NKp30; NCR3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Natural Cytotoxicity Triggering Receptor 3; Activating Natural Killer Receptor p30; Natural Killer Cell p30-Related Protein; NK-p30; NKp30; CD337; NCR3; 1C7; LY117; 1C7; DAAP-90L16.3; MALS\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O14931\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: O14931\u003c\/p\u003e\n\n\u003cp\u003eBackground: Natural Cytotoxicity Triggering Receptor 3; NCR3; also known as NKp30; or CD337; is a natural cytotoxicity receptor; expressed on subsets of human peripheral blood NK cells; involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive; but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity; and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-Gly135\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 14.74 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 25 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43083627069619,"sku":"PDMH100134-20","price":264.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43083627102387,"sku":"PDMH100134-100","price":418.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6aaf00c2-298f-4653-8c64-aa8254cfd40f.png?v=1708945532","url":"https:\/\/afsbio.com\/products\/recombinant-human-nkp30-ncr3-protein-his-tag-pdmh100134","provider":"AFSBio Inc.","version":"1.0","type":"link"}