{"product_id":"recombinant-human-nogo-receptor-ngr-protein-his-tag-pksh033418","title":"Recombinant Human Nogo Receptor\/NgR Protein (His Tag) - PKSH033418","description":"\u003cp\u003eRecombinant Human Nogo Receptor\/NgR Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH033418-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Nogo Receptor; NgR\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Reticulon-4 Receptor; Nogo Receptor; NgR; Nogo-66 Receptor; RTN4R; NOGOR\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9BZR6\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9BZR6\u003c\/p\u003e\n\n\u003cp\u003eBackground: Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo; myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG); NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally; NgR may play a role in regulating the function of gap junctions.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Cys27-Ser447\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46.3 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 45-72 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104249708723,"sku":"PKSH033418-50","price":350.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_700daf70-89de-45af-bac0-88af28867059.png?v=1709292900","url":"https:\/\/afsbio.com\/products\/recombinant-human-nogo-receptor-ngr-protein-his-tag-pksh033418","provider":"AFSBio Inc.","version":"1.0","type":"link"}