{"product_id":"recombinant-human-olfactomedin-4-olfm4-protein-rp01761","title":"Recombinant human Olfactomedin-4\/OLFM4 Protein - RP01761","description":"\u003cp\u003eRecombinant human Olfactomedin-4\/OLFM4 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01761-10, RP01761-20, RP01761-50, RP01761-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant human Olfactomedin-4\/OLFM4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp21-Gln510) of human Olfactomedin-4\/OLFM4 (Accession #NP_006409.3) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: GC1; OLM4; OlfD; GW112; hGC-1; hOLfD; UNQ362; bA209J19.1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q6UX06\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10562\u003c\/p\u003e\n\n\u003cp\u003eSpecies: human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Olfactomedin-4 (OLFM4), previously called GC-1 (G-CSF stimulated clone-1) is an secreted glycoprotein that is a member of the Olfactomedin\/Noelin family of protein. It is expressed in epithelial cells of the prostate, small intestine, colon, bone marrow, and in several cancers , and is up-regulated in epithelial cells during inflammation. Mature OLFM4 is a 490 amino acid (aa) protein that is secreted mainly in a polymeric form which is held together by disulfide bonds and carbohydrate interactions. Mature human OLFM4 shares 71% aa sequence identity with mature mouse and rat OLFM4. Olfactomedin-4 (OLFM4) interacts with cell surface lectins and cadherins, which helps cell adhesion and cell spreading of NIH3T3 and 293T\/17 cells. OLFM4 plays a critical role in regulating progression of prostate cancer and is also novel biomarker for triple-negative breast cancer.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: DLGDVGPPIPSPGFSSFPGVDSSSSFSSSSRSGSSSSRSLGSGGSVSQLFSNFTGSVDDRGTCQCSVSLPDTTFPVDRVERLEFTAHVLSQKFEKELSKVREYVQLISVYEKKLLNLTVRIDIMEKDTISYTELDFELIKVEVKEMEKLVIQLKESFGGSSEIVDQLEVEIRNMTLLVEKLETLDKNNVLAIRREIVALKTKLKECEASKDQNTPVVHPPPTPGSCGHGGVVNISKPSVVQLNWRGFSYLYGAWGRDYSPQHPNKGLYWVAPLNTDGRLLEYYRLYNTLDDLLLYINARELRITYGQGSGTAVYNNNMYVNMYNTGNIARVNLTTNTIAVTQTLPNAAYNNRFSYANVAWQDIDFAVDENGLWVIYSTEASTGNMVISKLNDTTLQVLNTWYTKQYKPSASNAFMVCGVLYATRTMNTRTEEIFYYYDTNTGKEGKLDIVMHKMQEKVQSINYNPFDQKLYVYNDGYLLNYDLSVLQKPQ\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198251524275,"sku":"RP01761-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198251557043,"sku":"RP01761-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198251589811,"sku":"RP01761-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198251622579,"sku":"RP01761-100","price":672.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_79d12f70-f6ee-454d-be8d-f0938988c3ad.png?v=1766959744","url":"https:\/\/afsbio.com\/products\/recombinant-human-olfactomedin-4-olfm4-protein-rp01761","provider":"AFSBio Inc.","version":"1.0","type":"link"}