{"product_id":"recombinant-human-omgp-omg-protein-aa-1-420-his-tagactive-pksh031717","title":"Recombinant Human OMGP\/OMG Protein (aa 1-420, His Tag)(Active) - PKSH031717","description":"\u003cp\u003eRecombinant Human OMGP\/OMG Protein (aa 1-420, His Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH031717-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: OMGP; OMG\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: OMGP\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: Cell culture; ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P23515\u003c\/p\u003e\n\n\u003cp\u003eAccession: P23515-1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Oligodendrocyte-myelin glycoprotein; also known as OMG and OMGP; is a cell membrane protein which contains eightLRR (leucine-rich) repeats. OMG \/ OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG \/ OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG \/ OMGP play roles in both the developing and adult central nervous system. OMG \/ OMGP participats in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR; the receptor for Nogo. This function requires its leucine-rich repeat domain; a highly conserved region in OMgp during mammal evolution. OMG \/ OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG \/ OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation; neuronal sprouting and myelination are crucial processes involved in brain development and regeneration after injury.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. Immobilized OMG (0.8 μg\/ml, 100 μl\/well) will mediate \u0026gt; 20% C6 cell adhesion.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Asn 420\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 97 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 120-130 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104353222835,"sku":"PKSH031717-50","price":1024.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2fe71c73-1ec5-4cb5-852f-8f6b5318a075.png?v=1709295014","url":"https:\/\/afsbio.com\/products\/recombinant-human-omgp-omg-protein-aa-1-420-his-tagactive-pksh031717","provider":"AFSBio Inc.","version":"1.0","type":"link"}