{"product_id":"recombinant-human-oncostatin-m-osm-protein-rp00054","title":"Recombinant Human Oncostatin-M\/OSM Protein - RP00054","description":"\u003cp\u003eRecombinant Human Oncostatin-M\/OSM Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00054-10, RP00054-20, RP00054-50, RP00054-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Oncostatin-M\/OSM Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala26-Arg221) of human Oncostatin-M\/OSM (Accession #NP_065391.1).\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: OSM, oncostatin-M\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P13725\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5008\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95% as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This protein is a member of the leukemia inhibitory factor\/oncostatin-M (LIF\/OSM) family. The preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.8-3.2 ng\/mL, corresponding to a specific activity of 3.12×10^5 -1.25×10^6 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 20mM Tris, 150mM NaCl, 5% glycerol, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: AAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198291894451,"sku":"RP00054-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198291927219,"sku":"RP00054-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198291959987,"sku":"RP00054-50","price":315.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198291992755,"sku":"RP00054-100","price":504.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_4c07cb69-4f91-4036-9758-3f70e4fb9652.png?v=1766960209","url":"https:\/\/afsbio.com\/products\/recombinant-human-oncostatin-m-osm-protein-rp00054","provider":"AFSBio Inc.","version":"1.0","type":"link"}