{"product_id":"recombinant-human-ox-2-mox1-cd200-protein-fc-tag-pksh032841","title":"Recombinant Human OX-2\/MOX1\/CD200 Protein (Fc Tag) - PKSH032841","description":"\u003cp\u003eRecombinant Human OX-2\/MOX1\/CD200 Protein (Fc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032841-10, PKSH032841-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: OX-2; MOX1; CD200\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: OX-2 Membrane Glycoprotein; CD200; MOX1; MOX2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P41217\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eAccession: P41217\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. It contains one Ig like V type domain and one Ig like C2 type domain in its extracelluar domain. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells; basophils; macrophages; and dendritic cells; which suggests myeloid cell regulation as the major function of CD200. CD200 and CD200R associate via their respective N-terminal Ig-like domains. In myeloid cells; CD200R initiates inhibitory signals following receptor-ligand contact. In T cells; CD200 functions as a co-stimulatory molecule independent of the CD28 pathway. In addition; CD200 also plays an important role in prevention of graft rejection; autoimmune diseases and spontaneous abortion.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gln31-Gly232\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 49.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 65-90 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068744302771,"sku":"PKSH032841-10","price":163.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068744335539,"sku":"PKSH032841-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_db5a62d0-bc00-4a78-9844-f69de44577b1.png?v=1708597295","url":"https:\/\/afsbio.com\/products\/recombinant-human-ox-2-mox1-cd200-protein-fc-tag-pksh032841","provider":"AFSBio Inc.","version":"1.0","type":"link"}