{"product_id":"recombinant-human-pak6-protein-his-tag-pdeh100365","title":"Recombinant Human PAK6 protein (His tag) - PDEH100365","description":"\u003cp\u003eRecombinant Human PAK6 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEH100365-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PAK6\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Serine\/threonine-protein kinase PAK 6; PAK6; p21-activated kinase 6 (PAK-6)\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9NQU5\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: signal Transduction; \u003cbr\u003e\nCancer; Cell Biology; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His \u0026amp; C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9NQU5\u003c\/p\u003e\n\n\u003cp\u003eBackground: As downstream targets of the Rho GTPases, the p21-activated kinase (PAK) family of serine\/threonine kinases regulates the organization of the actin cytoskeleton in mammalian cells. The PAK family is structurally categorized in two groups, each with three members: group I PAK1-3; and group II PAK4-6. PAK6 is expressed most highly in brain and testes, with lower levels in multiple tissues. Both MKK6 and p38 MAPK activate PAK6, suggesting a role for this kinase in the cellular stress response.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Cys 681\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 74.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 80 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43083553767603,"sku":"PDEH100365-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8fe8d2f5-1cbe-48f2-a6e4-456af621269f.png?v=1708944565","url":"https:\/\/afsbio.com\/products\/recombinant-human-pak6-protein-his-tag-pdeh100365","provider":"AFSBio Inc.","version":"1.0","type":"link"}