{"product_id":"recombinant-human-pd-1-pdcd1-cd279-protein-rp00067","title":"Recombinant Human PD-1\/PDCD1\/CD279 Protein - RP00067","description":"\u003cp\u003eRecombinant Human PD-1\/PDCD1\/CD279 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00067-10, RP00067-20, RP00067-50, RP00067-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human PD-1\/PDCD1\/CD279 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu25-Thr168) of human PD-1 (Accession #NP_005009.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PDCD1, CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1, programmed cell death 1, PD-1, CD279, PD1, SLEB2, hPD-1, hPD-l, hSLE1, PD-1\/CD279\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q15116\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5133\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE; ≥ 90 % as determined by HPLC.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This protein is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB\/c background developed dilated cardiomyopathy and died from congestive heart failure.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human PD-1 at 5 μg\/mL (100 μL\/well) can bind Recombinant Human PD-L1 with a linear range of 0.5-2 μg\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: LDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQT\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198292943027,"sku":"RP00067-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198292975795,"sku":"RP00067-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198293008563,"sku":"RP00067-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198293041331,"sku":"RP00067-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_801e0205-ca2b-40f2-9fab-2cfb5ad593f7.png?v=1766960222","url":"https:\/\/afsbio.com\/products\/recombinant-human-pd-1-pdcd1-cd279-protein-rp00067","provider":"AFSBio Inc.","version":"1.0","type":"link"}