{"product_id":"recombinant-human-pd-l2-cd273-protein-his-avi-tag-pksh033795","title":"Recombinant Human PD-L2\/CD273 Protein (His \u0026 Avi Tag) - PKSH033795","description":"\u003cp\u003eRecombinant Human PD-L2\/CD273 Protein (His \u0026amp; Avi Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033795-20, PKSH033795-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PD-L2; CD273\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Programmed Cell Death 1 Ligand 2; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; Programmed Death Ligand 2; Butyrophilin B7-DC; B7-DC; CD273; PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His-Avi\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9BQ51\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9BQ51\u003c\/p\u003e\n\n\u003cp\u003eBackground: Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN\/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart; placenta; pancreas; lung and liver; it is weakly expressed in the spleen; lymph nodes; and thymus. PDCD1LG2 is involved in the costimulatory signal; essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu20-Pro219\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 25.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 38-60 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43113992421555,"sku":"PKSH033795-20","price":478.8,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43113992454323,"sku":"PKSH033795-100","price":1293.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a13e559f-20a4-4023-8342-1333b7935741.png?v=1709549851","url":"https:\/\/afsbio.com\/products\/recombinant-human-pd-l2-cd273-protein-his-avi-tag-pksh033795","provider":"AFSBio Inc.","version":"1.0","type":"link"}