{"product_id":"recombinant-human-pdap1-pap-protein-his-tag-pksh032868","title":"Recombinant Human PDAP1\/PAP Protein (His Tag) - PKSH032868","description":"\u003cp\u003eRecombinant Human PDAP1\/PAP Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032868-10, PKSH032868-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PDAP1; PAP\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 28 kDa Heat- and Acid-Stable Phosphoprotein; PDGF-Associated Protein; PAP; PDGFA-Associated Protein 1; PAP1; PDAP1; HASPP28\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q13442\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q13442\u003c\/p\u003e\n\n\u003cp\u003eBackground: Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Lys181\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 100mM NaCl, 0.1mM PMSF, 2mM DTT, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 22.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 30 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068750528691,"sku":"PKSH032868-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068750561459,"sku":"PKSH032868-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2082f788-f1f9-4588-ab39-bd752953c1bb.png?v=1708597340","url":"https:\/\/afsbio.com\/products\/recombinant-human-pdap1-pap-protein-his-tag-pksh032868","provider":"AFSBio Inc.","version":"1.0","type":"link"}