{"product_id":"recombinant-human-peroxiredoxin-3-prdx3-protein-pksh032882","title":"Recombinant Human Peroxiredoxin-3\/PRDX3 Protein - PKSH032882","description":"\u003cp\u003eRecombinant Human Peroxiredoxin-3\/PRDX3 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032882-10, PKSH032882-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Peroxiredoxin-3; PRDX3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Thioredoxin-Dependent Peroxide Reductase Mitochondrial; Antioxidant Protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog; PRDX3; AOP1\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P30048\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cell biology; Cardiovascular; Neuroscience; Cancer; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: None\u003c\/p\u003e\n\n\u003cp\u003eAccession: P30048\u003c\/p\u003e\n\n\u003cp\u003eBackground: Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC\/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Pro63-Gln256\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 21.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 25 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068755476659,"sku":"PKSH032882-10","price":368.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068755509427,"sku":"PKSH032882-50","price":684.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9f48cbe1-f4ac-4d38-bb42-7d06c1385d09.png?v=1708597374","url":"https:\/\/afsbio.com\/products\/recombinant-human-peroxiredoxin-3-prdx3-protein-pksh032882","provider":"AFSBio Inc.","version":"1.0","type":"link"}