{"product_id":"recombinant-human-pfk1-pfkm-protein-his-gst-tag-pksh030320","title":"Recombinant Human PFK1\/PFKM Protein (His \u0026 GST Tag) - PKSH030320","description":"\u003cp\u003eRecombinant Human PFK1\/PFKM Protein (His \u0026amp; GST Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH030320-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PFK1, PFKM\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 6-phosphofructokinase, muscle type, Phosphofructo-1-kinase isozyme A, Phosphofructokinase 1, Phosphohexokinase, PFKM, PFKX, ATP-PFK, GSD7, PFK-1, PFK1, PFKA, PPP1R122\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P08237\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: Baculovirus-Insect Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His \u0026amp; GST\u003c\/p\u003e\n\n\u003cp\u003eAccession: P08237-1\u003c\/p\u003e\n\n\u003cp\u003eBackground: PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1, 6-bisphosphate (through PFK-1), fructose 2, 6-bisphosphate (through PFK-2) and ADP. It is a muscle-type isozyme. There are three phosphofructokinase isozymes in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Mutations in PFK1 gene have been related with glycogen storage disease type VII, also identified as Tarui disease.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Thr 2-Val 780\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as sterile solution of 20mM Tris, 500mM NaCl, pH 8.5, 10% glycerol\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 112.9 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 113 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μg","offer_id":43155062915251,"sku":"PKSH030320-50","price":1127.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e08072d0-ada5-41ee-bc75-09c47917ad63.png?v=1710438225","url":"https:\/\/afsbio.com\/products\/recombinant-human-pfk1-pfkm-protein-his-gst-tag-pksh030320","provider":"AFSBio Inc.","version":"1.0","type":"link"}