{"product_id":"recombinant-human-phospholipase-a2-pla2g1b-protein-rp03277","title":"Recombinant Human Phospholipase A2\/PLA2G1B Protein - RP03277","description":"\u003cp\u003eRecombinant Human Phospholipase A2\/PLA2G1B Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP03277-10, RP03277-20, RP03277-50, RP03277-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Phospholipase A2\/PLA2G1B Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ser148) of human Phospholipase A2\/PLA2G1B (Accession #NP_000919.1) fused with His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Phospholipase A2; PLA2G1B; PLA2; PLA2A; PPLA2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P04054\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5319\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Phospholipase A2 (PLA2) plays crucial roles in diverse cellular responses, including phospholipid digestion and metabolism, host defense and signal transduction. PLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic acid, platelet-activating factor (PAF) when the sn-1 position of the phosphatidylcholine contains an alkyl ether linkage and some bioactive lysophospholipids, such as lysophosphatidic acid (lysoPA).\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its ability to hydrolyze 1-Hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphomethanol. The specific activity is \u0026gt;2500 pmol\/min\/μg.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 10 mM Tris, 5 mM CaCl2, pH 8.0. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198343372979,"sku":"RP03277-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198343405747,"sku":"RP03277-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198343438515,"sku":"RP03277-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198343471283,"sku":"RP03277-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_66051a0b-4820-435f-852e-9730eea4795c.png?v=1766960828","url":"https:\/\/afsbio.com\/products\/recombinant-human-phospholipase-a2-pla2g1b-protein-rp03277","provider":"AFSBio Inc.","version":"1.0","type":"link"}