{"product_id":"recombinant-human-pigr-sc-protein-his-tag-pdeh100152","title":"Recombinant Human PIGR\/SC protein (His tag) - PDEH100152","description":"Recombinant Human PIGR\/SC protein (His tag)\n\nSize: 100μg\n\nCatalogue Numbers: PDEH100152-100\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: PIGR; SC\n\nTarget Synonym: Polymeric Immunoglobulin Receptor; PIgR; Poly-Ig Receptor; PIGR\n\nUNIProt ID: P01833\n\nResearch Areas: immunology\n\nTarget Species: Human\n\nExpression Host: E.coli\n\nFusion Tag: N-His\n\nAccession: P01833\n\nBackground: Polymeric immunoglobulin receptor, also known as  PIGR, is a member of the immunoglobulin superfamily  and a  Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of  IgA  and  IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.\n\nSequence: Lys 19-Ala 561\n\nPurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile PBS, pH 7.4.\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: Please contact us for more information.\n\nCalculated MW: 59.62 kDa\n\nObserved MW: 59 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43072323584179,"sku":"PDEH100152-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_43e17ca3-31ad-47f1-9438-9c3b76b6b39e.png?v=1708685512","url":"https:\/\/afsbio.com\/products\/recombinant-human-pigr-sc-protein-his-tag-pdeh100152","provider":"AFSBio Inc.","version":"1.0","type":"link"}