{"product_id":"recombinant-human-pik3ip1-protein-his-tag-pksh032898","title":"Recombinant Human PIK3IP1 Protein (His Tag) - PKSH032898","description":"\u003cp\u003eRecombinant Human PIK3IP1 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032898-10, PKSH032898-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PIK3IP1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Kringle domain-containing protein HGFL; PIK3IP1; HGFL\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q96FE7\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; immunology;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q96FE7\u003c\/p\u003e\n\n\u003cp\u003eBackground: Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. The gene encoding PIK3IP1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ser22-Thr168\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 10mM reduced Glutathione, PH8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 16.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 11\u0026amp;30-40 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068761374899,"sku":"PKSH032898-10","price":163.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068761407667,"sku":"PKSH032898-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_f4ae2fa9-ff2e-4eb0-80f0-e95214ae9c85.png?v=1708597419","url":"https:\/\/afsbio.com\/products\/recombinant-human-pik3ip1-protein-his-tag-pksh032898","provider":"AFSBio Inc.","version":"1.0","type":"link"}