{"product_id":"recombinant-human-platelet-derived-growth-factor-bb-rhupdgf-bb-pr1110","title":"Recombinant Human Platelet-derived growth factor -BB (rHuPDGF-BB) - PR1110","description":"\u003cp\u003eRecombinant Human Platelet-derived growth factor -BB (rHuPDGF-BB)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR1110-2, PR1110-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 12.4 KDa, a disulfide-linked homodimeric protein containing two 109 amino acid residues polypeptide (B chain).\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard.The ED50 as determined by the dose-dependent stimulation of the proliferation of murine Balb\/c 3T3 cells is ≤ 3.0ng\/ml, corresponding to a specific activity of ≥ 3.3×105 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPIFKKAt VT LEDHLACKCE \u003cbr\u003e\n t VAAARPVT\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/μg of rHuPDGF-BB as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Human Platelet-derived growth factor -BB \u003cbr\u003e\n Platelet-derived growth factor (PDGF) presenting in serum but absent from plasma was first discovered in animal study by Lynch and co-workers in the late 1980s. It is a disulfide-linked dimer consisting of two peptides-chain A and chain B. PDGF has three subforms: PDGF-AA, PDGF-BB, PDGF-AB. It is involved in a number of biological processes, including hyperplasia, embryonic neuron development, chemotaxis, and respiratory tubule epithelial cell development. The function of PDGF is mediated by two receptors (PDGFR-α and PDGFR-β).\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882220359859,"sku":"PR1110-2","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"10µg","offer_id":42882220392627,"sku":"PR1110-10","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5acb7f73-0f6c-474e-b400-4d16527fd5e6.jpg?v=1702049505","url":"https:\/\/afsbio.com\/products\/recombinant-human-platelet-derived-growth-factor-bb-rhupdgf-bb-pr1110","provider":"AFSBio Inc.","version":"1.0","type":"link"}