{"product_id":"recombinant-human-pmkase-pmvk-protein-rp02879lq","title":"Recombinant Human PMKase\/PMVK Protein - RP02879LQ","description":"\u003cp\u003eRecombinant Human PMKase\/PMVK Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: RP02879LQ-10, RP02879LQ-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human PMKase\/PMVK Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Leu192) of human PMKase\/PMVK (Accession #NP_006547.1) fused with a 6×His tag at the N-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PMVK, HUMPMKI, PMK, PMKA, PMKASE, POROK1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q15126\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10654\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney; it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: N-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198356185267,"sku":"RP02879LQ-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198356218035,"sku":"RP02879LQ-50","price":616.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_09684677-7296-4f0e-93f2-076935044894.png?v=1766961062","url":"https:\/\/afsbio.com\/products\/recombinant-human-pmkase-pmvk-protein-rp02879lq","provider":"AFSBio Inc.","version":"1.0","type":"link"}