{"product_id":"recombinant-human-pmm1-protein-his-tag-pksh032893","title":"Recombinant Human PMM1 Protein (His Tag) - PKSH032893","description":"\u003cp\u003eRecombinant Human PMM1 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032893-10, PKSH032893-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PMM1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Phosphomannomutase 1; PMM 1; PMMH-22; PMM1; PMMH22\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q92871\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q92871\u003c\/p\u003e\n\n\u003cp\u003eBackground: Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1, 6 bisphosphate in ischemic brain.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Ala262\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 30.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 49 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068759277747,"sku":"PKSH032893-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068759310515,"sku":"PKSH032893-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_778b8cf6-adab-4cd3-a552-d2bb32402bf2.png?v=1708597401","url":"https:\/\/afsbio.com\/products\/recombinant-human-pmm1-protein-his-tag-pksh032893","provider":"AFSBio Inc.","version":"1.0","type":"link"}