{"product_id":"recombinant-human-pold2-protein-his-tag-pksh032361","title":"Recombinant Human POLD2 Protein (His Tag) - PKSH032361","description":"\u003cp\u003eRecombinant Human POLD2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032361-10, PKSH032361-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: POLD2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: DNA Polymerase Delta Subunit 2; DNA Polymerase Delta Subunit p50; POLD2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P49005\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: epigenetics and nuclear signal\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P49005\u003c\/p\u003e\n\n\u003cp\u003eBackground: DNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta\/II small subunit family. POLD2 can form a heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. POLD2 possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. POLD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA).\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Pro469\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 52.3 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 56 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43092770848947,"sku":"PKSH032361-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43092770881715,"sku":"PKSH032361-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c02abf90-b086-4fac-a056-b6dc362fce49.png?v=1709119633","url":"https:\/\/afsbio.com\/products\/recombinant-human-pold2-protein-his-tag-pksh032361","provider":"AFSBio Inc.","version":"1.0","type":"link"}