{"product_id":"recombinant-human-pp2a-cα-ppp2ca-protein-his-tag-pdeh100357","title":"Recombinant Human PP2A-Cα\/PPP2CA protein (His tag) - PDEH100357","description":"\u003cp\u003eRecombinant Human PP2A-Cα\/PPP2CA protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEH100357-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PP2A-Cα; PPP2CA\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PPP2CA; \u003cbr\u003e\nPP2A-alpha; Replication protein C (RP-C); PPP2CA\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P67775\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Signal Transduction; \u003cbr\u003e\nCell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His \u0026amp; C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P67775\u003c\/p\u003e\n\n\u003cp\u003eBackground: Protein Phosphatase 2A (PP2A) is an enzyme that removes phosphates covalently attached to serine and threonine residues in proteins. It contains three subunits; a catalytic subunit C (PP2Ac), an assembly\/structural subunit A (PP2Aa), and a regulatory subunit B (PP2Ab). PP2A is a ubiquitous enzyme that plays a role in regulating many cellular activities varying from ion transport in erythrocytes to suppressing tumor growth. Binding of the SV40 small T antigen to the PP2A phosphatase complex is known to cause oncogenic transformation.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Leu 309\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 39.3 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 40 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43083552686259,"sku":"PDEH100357-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_63db2b55-96e0-4d36-b5b7-50bddaec369d.png?v=1708944543","url":"https:\/\/afsbio.com\/products\/recombinant-human-pp2a-c%ce%b1-ppp2ca-protein-his-tag-pdeh100357","provider":"AFSBio Inc.","version":"1.0","type":"link"}