{"product_id":"recombinant-human-ppiase-fkbp7-protein-aa-24-222-his-tag-pksh032878","title":"Recombinant Human PPIase\/FKBP7 Protein (aa 24-222, His Tag) - PKSH032878","description":"\u003cp\u003eRecombinant Human PPIase\/FKBP7 Protein (aa 24-222, His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032878-10, PKSH032878-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PPIase; FKBP7\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Peptidyl-Prolyl Cis-Trans Isomerase FKBP7; PPIase FKBP7; 23 kDa FK506-Binding Protein; 23 kDa FKBP; FKBP-23; FK506-Binding Protein 7; FKBP-7; Rotamase; FKBP7; FKBP23\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9Y680\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9Y680\u003c\/p\u003e\n\n\u003cp\u003eBackground: Peptidyl-Prolyl Cis-Trans Isomerase FKBP7 (FKBP7) is a member of the FKBP-type peptidyl-prolyl cis\/trans isomerase (PPIase) family. FKBP7 contains two EF-hand domains and one PPIase FKBP-type domain. FKBP7 exhibits PPIase activity and function as molecular chaperones. In addition, FKBP7 accelerates the folding of proteins during protein synthesis. It has been shown that Hsp90 complex to the nucleus bind its PPIase domain to cytoplasmic dynein, the motor protein responsible for retrograde movement along microtubules.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gln24-Leu222\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM GaCl2, 10%Glycerol, pH7.5.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 23.9 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 20-26 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068753576115,"sku":"PKSH032878-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068753608883,"sku":"PKSH032878-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8319316a-54d0-4f89-ace9-6aad28a36da0.png?v=1708597362","url":"https:\/\/afsbio.com\/products\/recombinant-human-ppiase-fkbp7-protein-aa-24-222-his-tag-pksh032878","provider":"AFSBio Inc.","version":"1.0","type":"link"}