{"product_id":"recombinant-human-ppiase-ppil1-protein-aa-1-166-his-tag-pksh033304","title":"Recombinant Human PPIase\/PPIL1 Protein (aa 1-166, His Tag) - PKSH033304","description":"\u003cp\u003eRecombinant Human PPIase\/PPIL1 Protein (aa 1-166, His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033304-10, PKSH033304-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PPIase; PPIL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1; PPIase; Rotamase PPIL1; PPIL1; CYPL1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; epigenetics and nuclear signal; immunology;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9Y3C6\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9Y3C6\u003c\/p\u003e\n\n\u003cp\u003eBackground: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ; skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Gly166\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 20.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 19 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113944121523,"sku":"PKSH033304-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113944154291,"sku":"PKSH033304-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_311b99c9-0eb8-4995-83f0-87092d3bbfad.png?v=1709549030","url":"https:\/\/afsbio.com\/products\/recombinant-human-ppiase-ppil1-protein-aa-1-166-his-tag-pksh033304","provider":"AFSBio Inc.","version":"1.0","type":"link"}