{"product_id":"recombinant-human-prdx5-isoform-cytoplasmic-peroxisomal-protein-his-tag-pksh031176","title":"Recombinant Human PRDX5 Isoform cytoplasmic + peroxisomal Protein (His Tag) - PKSH031176","description":"\u003cp\u003eRecombinant Human PRDX5 Isoform cytoplasmic + peroxisomal Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH031176-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PRDX5, Peroxiredoxin 5\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, prx-V, PRXV, SBBI10\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P30044\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P30044-2\u003c\/p\u003e\n\n\u003cp\u003eBackground: Peroxiredoxin-5, also known as Alu corepressor 1, Antioxidant enzyme B166, Liver tissue 2D-page spot 71B, Peroxisomal antioxidant enzyme, Thioredoxin peroxidase PMP20, Thioredoxin reductase, PRDX5 and ACR1, is cytoplasm protein which belongs to the peroxiredoxin 2 family. Peroxiredoxin-5 \/ PRDX5 reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-5 \/ PRDX5 is involved in intracellular redox signaling. The Peroxiredoxins \/ Prx are a family of 25 kDa peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins \/ Prx family is divided into six groups ( PRDX1, PRDX2, PRDX3, PRDX4, PRDX5, PRDX6 ) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins \/ Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins \/ Prx has a proliferative effect and may be related to cancer development or progression.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 53-Leu 214\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile 50mM Tris, pH 7.5\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 18.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 18.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43155076350131,"sku":"PKSH031176-100","price":1197.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_aaabec9f-cdf8-424e-bc3d-13538b39ab45.png?v=1710438572","url":"https:\/\/afsbio.com\/products\/recombinant-human-prdx5-isoform-cytoplasmic-peroxisomal-protein-his-tag-pksh031176","provider":"AFSBio Inc.","version":"1.0","type":"link"}